Iba1 Polyclonal Antibody
Product details
Background:
This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016],
Specifications
| Target | AIF1 |
| Reactivity | Human, Rat, Mouse |
| Applications | WB, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 16kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate | |
| Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000;ELISA 1:5000;IF 1:100-300;Not yet tested in other applications. |
| Composition | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Source | |
| Purification Process | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Purity | |
| Storage Condition | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Sequence | |
| Specificity | AIF1 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | AIF1 G1 IBA1 |
| Protein Name | Allograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1) (Protein G1) |
| Alias | |
| Organism-1 | Human |
| Gene ID-1 | 199 |
| SwissProt-1 | P55008 |
| Organism-2 | Mouse |
| Gene ID-2 | |
| SwissProt-2 | O70200 |
| Organism-3 | Rat |
| Gene ID-3 | |
| SwissProt-3 | P55009 |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Cellular Localization | Cytoplasm, cytoskeleton . Cell projection, ruffle membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, phagocytic cup . Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis. . |
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