IFT74 rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | IFT74 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 66kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human IFT74 |
| Specificity | This antibody detects endogenous levels of IFT74 at Human, Mouse |
| Gene Name | IFT74 CCDC2 CMG1 |
| Protein Name | Intraflagellar transport protein 74 homolog (Capillary morphogenesis gene 1 protein) (CMG-1) (Coiled-coil domain-containing protein 2) |
| Other Name | |
| Species | Human |
| Gene ID | 80173 |
| Uniprot | Q96LB3, |
| Species.1 | Mouse |
| Gene ID.1 | 67694 |
| Uniprot.1 | Q8BKE9 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell projection, cilium. Cytoplasmic vesicle. Localizes along primary cilia at interphase and around the basal body/centriole at interphase and mitosis. |
| Tissue Expression | Highly expressed in adult and fetal kidney and expressed at lower level in adult heart, placenta, lung, liver and pancreas, and in fetal heart, lung and liver. Little to no expression was detected in adult brain and skeletal muscle or in fetal brain, thymus and spleen. |
| Signaling_pathway | |
| Research Areas | |
| Function | Component of the intraflagellar transport (IFT) complex B: together with IFT81, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds beta-tubulin via its basic region. Required for ciliogenesis. |
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