Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human IFT88
Specificity
This antibody detects endogenous levels of IFT88 at Human, Mouse
Gene Name
IFT88 TG737 TTC10
Protein Name
Intraflagellar transport protein 88 homolog (Recessive polycystic kidney disease protein Tg737 homolog) (Tetratricopeptide repeat protein 10) (TPR repeat protein 10)
Other Name
Species
Human
Gene ID
8100
Uniprot
Q13099,
Species.1
Mouse
Gene ID.1
21821
Uniprot.1
Q61371
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cell projection, cilium . Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm . Cell projection, cilium, flagellum . Colocalizes with ENTR1 and gamma-tubulin at the basal body of primary cilia. Colocalizes with ENTR1 and pericentrin at the centrosome. .
Tissue Expression
Expressed in the heart, brain, liver, lung, kidney, skeletal muscle and pancreas.
Signaling_pathway
Research Areas
Function
Involved in primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment.