IGFBP6 Polyclonal Antibody
Ucallm_WP15407-50
Price range: $268.00 through $328.00
Product details
Background:
function:IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors., PTM:O-linked glycans consist of hexose (probably Gal), N-acetylhexosamine (probably GalNAc) and sialic acid residues. Major glycoforms consist of 8-16 monosaccharides (by homology to IGFBP6 expressed recombinantly in CHO cells)., similarity:Contains 1 IGFBP N-terminal domain., similarity:Contains 1 thyroglobulin type-1 domain.,
Specifications
| Size | 50μL/100μL |
| Target | IGFBP6 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 25kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human IGFBP6. AA range:101-150 |
| Specificity | IGFBP6 Polyclonal Antibody detects endogenous levels of IGFBP6 protein. |
| Gene Name | IGFBP6 |
| Protein Name | Insulin-like growth factor-binding protein 6 |
| Other Name | IGFBP6; / IBP6; / Insulin-like growth factor-binding protein 6; / IBP-6; / IGF-binding protein 6; / IGFBP-6 |
| Species | Human |
| Gene ID | 3489 |
| Uniprot | P24592, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P47880 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted . |
| Tissue Expression | Cerebrospinal fluid,Fibroblast,Osteosarcoma,Pancreas,Placen |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.,PTM:O-linked glycans consist of hexose (probably Gal), N-acetylhexosamine (probably GalNAc) and sialic acid residues. Major glycoforms consist of 8-16 monosaccharides (by homology to IGFBP6 expressed recombinantly in CHO cells).,similarity:Contains 1 IGFBP N-terminal domain.,similarity:Contains 1 thyroglobulin type-1 domain., |
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