Product details
Background:
IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20 (IL20; MIM 605619) (Blumberg et al., 2001 [PubMed 11163236]).[supplied by OMIM, Feb 2009],
IL-20Rβ Polyclonal Antibody
Ucallm_WP12818-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | IL-20Rβ |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 35kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human IL20RB. AA range:141-190 |
| Specificity | IL-20Rβ Polyclonal Antibody detects endogenous levels of IL-20Rβ protein. |
| Gene Name | IL20RB |
| Protein Name | Interleukin-20 receptor subunit beta |
| Other Name | IL20RB; / DIRS1; / Interleukin-20 receptor subunit beta; / IL-20 receptor subunit beta; / IL-20R-beta; / IL-20RB; / IL-20R2 |
| Species | Human |
| Gene ID | 53833 |
| Uniprot | Q6UXL0 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Membrane; Single-pass type I membrane protein . |
| Tissue Expression | Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin. |
| Signaling_pathway | Environmental Information Processing >> Signal transduction >> JAK-STAT signaling pathway;Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction;Environmental Information Processing >> Signaling molecules and interaction >> Viral protein interaction with cytokine and cytokine receptor |
| Research Areas | >>Cytokine-cytokine receptor interaction; / >>Viral protein interaction with cytokine and cytokine receptor; / >>JAK-STAT signaling pathway |
| Function | Function:The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.,similarity:Belongs to the type II cytokine receptor family.,similarity:Contains 2 fibronectin type-III domains.,subunit:Heterodimer with IL20RA and heterodimer with IL22RA1.,tissue specificity:Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin., |
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