SKU: WP0657 Categories: ,

ILRL2 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP0657-100
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Product details

Background:

The protein encoded by this gene is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. This gene and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetILRL2
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)63kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 330-410
SpecificityILRL2 Polyclonal Antibody detects endogenous levels of protein.
Gene NameIL1RL2 IL1RRP2
Protein NameInterleukin-1 receptor-like 2 (Interleukin-1 receptor-related protein 2) (IL-1Rrp2) (IL1R-rp2)
Other Name
SpeciesHuman
Gene ID8808
UniprotQ9HB29,
Species.1Mouse
Gene ID.1
Uniprot.1Q9ERS7,
Species.2Rat
Gene ID.2
Uniprot.2Q62929
Cellular LocalizationMembrane; Single-pass type I membrane protein .
Tissue ExpressionExpressed in synovial fibroblasts and articular chondrocytes. Expressed in keratinocytes and monocyte-derived dendritic cells. Expressed in monocytes and myeloid dendritic cells; at protein level.
Signaling_pathwayEnvironmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
Research Areas>>Cytokine-cytokine receptor interaction
FunctionFunction:Receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B.,miscellaneous:Does not bind interleukin 1 alpha (IL-1A) or interleukin 1 beta (IL-1B).,similarity:Belongs to the interleukin-1 receptor family.,similarity:Contains 1 TIR domain.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,
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