Price range: $268.00 through $328.00
Background:
The mitochondrial inner membrane peptidase (IMP) complex generates mature, active proteins in the mitochondrial intermembrane space by proteolytically removing the mitochondrial targeting presequence of nuclear-encoded proteins. IMP1 and IMP2 (IMMP2L; MIM 605977) are the catalytic subunits of the IMP complex (Burri et al., 2005 [PubMed 15814844]).[supplied by OMIM, Sep 2008],
| Size | 50μL/100μL |
| Target | IMP1L |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 18kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 70-150 |
| Specificity | IMP1L Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | IMMP1L |
| Protein Name | Mitochondrial inner membrane protease subunit 1 (IMP1-like protein) |
| Other Name | |
| Species | Human |
| Gene ID | 196294 |
| Uniprot | Q96LU5, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9CQU8 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Mitochondrion inner membrane . |
| Tissue Expression | Cerebellum,Eye, |
| Signaling_pathway | |
| Research Areas | >>Protein export |
| Function | Function:Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.,similarity:Belongs to the peptidase S26 family. IMP1 subfamily.,subunit:Heterodimer of 2 subunits, IMMPL1 and IMMPL2., |
