Imp3 Polyclonal Antibody
Product details
Background:
This gene encodes the human homolog of the yeast Imp3 protein. The protein localizes to the nucleoli and interacts with the U3 snoRNP complex. The protein contains an S4 domain. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | IMP3 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, ELISA |
| MW(Calculated) | |
| MW(Observed) | 25kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:500-2000; ELISA 1:10000-20000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthetic peptide from human protein at AA range: 135-184 |
| Specificity | The antibody detects endogenous Imp3 protein |
| Gene Name | IMP3 C15orf12 MRPS4 |
| Protein Name | U3 small nucleolar ribonucleoprotein protein IMP3 |
| Other Name | IMP 3; / IMP-3; / U3 small nucleolar ribonucleoprotein protein IMP3; / C15orf12; / MRPS4; / U3 snoRNP protein IMP3; / BRMS2 |
| Species | Human |
| Gene ID | 55272 |
| Uniprot | Q9NV31, |
| Species.1 | Mouse |
| Gene ID.1 | 102462 |
| Uniprot.1 | Q921Y2 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus, nucleolus . |
| Tissue Expression | Eye,Placenta,Uterus, |
| Signaling_pathway | |
| Research Areas | >>Ribosome biogenesis in eukaryotes |
| Function | Function:Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.,similarity:Belongs to the ribosomal protein S4P family.,similarity:Contains 1 S4 RNA-binding domain.,subunit:Component of a heterotrimeric complex containing IMP3, IMP4 and MPHOSPH10. Interacts with MPHOSPH10., |
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