Product details
Background:
INMT rabbit pAb
Ucallm_WP8211-50
Price range: $268.00 through $328.00
Specifications
| Target | INMT |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 29kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Modification | |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human INMT |
| Sequence | |
| Specificity | This antibody detects endogenous levels of INMT at Human, Mouse |
| Gene Name | INMT |
| Protein Name | Indolethylamine N-methyltransferase (Indolamine N-methyltransferase) (Aromatic alkylamine N-methyltransferase) (Amine N-methyltransferase) (Arylamine N-methyltransferase) (Thioether S-methyltransferase) (TEMT) |
| Other Name | |
| Species | Human |
| Gene ID-1 | 11185 |
| Uniprot | O95050, |
| Species.1 | Mouse |
| Gene ID-2 | 21743 |
| Uniprot.1 | P40936 |
| Species.2 | |
| Gene ID-3 | |
| Uniprot.2 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Background | |
| Cellular Localization | Cytoplasm . |
| Tissue Expression | Widely expressed. The highest levels were in thyroid, adrenal gland, adult and fetal lung. Intermediate levels in heart, placenta, skeletal muscle, testis, small intestine, pancreas, stomach, spinal cord, lymph node and trachea. Very low levels in adult and fetal kidney and liver, in adult spleen, thymus, ovary, colon and bone marrow. Not expressed in peripheral blood leukocytes and brain. |
| Signaling_pathway | |
| Research Areas | |
| Function | Functions as thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2-methylthioethanol, methyl-n-propyl sulfide and diethyl sulfide. Plays an important role in the detoxification of selenium compounds (By similarity). Catalyzes the N-methylation of tryptamine and structurally related compounds. |
| RRID |
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