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INPP5A rabbit pAb
Ucallm_WP7578-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | INPP5A |
| Reactivity | Human |
| Applications | WB |
| MW(Calculated) | 45kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human INPP5A |
| Specificity | This antibody detects endogenous levels of INPP5A at Human |
| Gene Name | INPP5A |
| Protein Name | Type I inositol 1,4,5-trisphosphate 5-phosphatase (5PTase) (EC 3.1.3.56) |
| Other Name | |
| Species | Human |
| Gene ID | 3632 |
| Uniprot | Q14642 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Lipid-anchor . Cell projection, dendrite . |
| Tissue Expression | Predominantly expressed in heart, brain, and skeletal muscle (PubMed:8006039). In brain; high level in Purkinje cells (PubMed:8013665). |
| Signaling_pathway | Organismal Systems >> Endocrine system >> Insulin signaling pathway |
| Research Areas | |
| Function | Phosphatase that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate, and inositol 1,3,4,5-tetrasphosphate to inositol 1,3,4-trisphosphate . Plays a crucial role in the survival of cerebellar Purkinje cells (By similarity). |
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