Product details
Background:
catalytic activity:1D-myo-inositol 1, 3, 4, 5-tetrakisphosphate + H(2)O = 1D-myo-inositol 1, 3, 4-trisphosphate + phosphate., catalytic activity:D-myo-inositol 1, 4, 5-trisphosphate + H(2)O = myo-inositol 1, 4-bisphosphate + phosphate., domain:The 5 Arg-Ser-Xaa-Ser-Xaa-Xaa (RSXSXX) motifs may constitute binding sites for the 14-3-3 protein., function:Inositol 5-phosphatase, which converts inositol 1, 4, 5-trisphosphate to inositol 1, 4-bisphosphate. Also converts phosphatidylinositol 4, 5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1, 3, 4, 5-tetrakisphosphate to inositol 1, 3, 4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles., PTM:Phosphorylated at Ser/Thr residues., similarity:Belongs to the inositol-1, 4, 5-trisphosphate 5-phosphatase type II family., subcellular location:Predominantly localized to membrane ruffles.,
