Name: IPMK Polyclonal Antibody
SKU: WP12859
Price: 268 USD
Availability: InStock

IPMK Polyclonal Antibody

Ucallm_WP12859-50

Price range: $268.00 through $328.00

Size

100μl

50μl

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SKU: WP12859-100

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Product details

Background:

This gene encodes a member of the inositol phosphokinase family. The encoded protein has 3-kinase, 5-kinase and 6-kinase activities on phosphorylated inositol substrates. The encoded protein plays an important role in the biosynthesis of inositol 1, 3, 4, 5, 6-pentakisphosphate, and has a preferred 5-kinase activity. This gene may play a role in nuclear mRNA export. Pseudogenes of this gene are located on the long arm of chromosome 13 and the short arm of chromosome 19. [provided by RefSeq, Dec 2010],

Specifications

Size	50μL/100μL
Target	IPMK
Reactivity	Human, Mouse, Rat, Monkey
Applications	WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)	47kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human IPMK. AA range:311-360
Specificity	IPMK Polyclonal Antibody detects endogenous levels of IPMK protein.
Gene Name	IPMK
Protein Name	Inositol polyphosphate multikinase
Other Name	IPMK; / IMPK; / Inositol polyphosphate multikinase; / Inositol 1; / 3,4,6-tetrakisphosphate 5-kinase
Species	Human
Gene ID	253430
Uniprot	Q8NFU5,
Species.1	Mouse
Gene ID.1	69718
Uniprot.1	Q7TT16,
Species.2	Rat
Gene ID.2	171458
Uniprot.2	Q99NI4
Cellular Localization	Nucleus .
Tissue Expression	Ubiquitous, with the highest expression in skeletal muscle, liver, placenta, lung, peripheral blood leukocytes, kidney, spleen and colon.
Signaling_pathway
Research Areas	>>Inositol phosphate metabolism; / >>Metabolic pathways; / >>Phosphatidylinositol signaling system
Function	Catalytic activity:ATP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate.,Catalytic activity:ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate.,Function:Inositol phosphate kinase with a broad substrate specificity. Has a preference for inositol-1,4,5-trisphosphate (Ins(1,4,5)P3) and inositol 1,3,4,6-tetrakisphosphate (Ins(1,3,4,6)P4).,similarity:Belongs to the inositol phosphokinase (IPK) family.,tissue specificity:Ubiquitous, with the highest expression in skeletal muscle, liver, placenta, lung, peripheral blood leukocytes, kidney, spleen and colon.,