IQEC1 rabbit pAb
Ucallm_WP3671-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | IQEC1 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | |
| MW(Observed) | 105kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human IQEC1 AA range: 693-743 |
| Specificity | This antibody detects endogenous levels of IQEC1 at Human/Mouse |
| Gene Name | IQSEC1 ARFGEP100 BRAG2 KIAA0763 |
| Protein Name | IQEC1 |
| Other Name | IQ motif and SEC7 domain-containing protein 1; / ADP-ribosylation factors guanine nucleotide-exchange protein 100; / ADP-ribosylation factors guanine nucleotide-exchange protein 2; / Brefeldin-resistant Arf-GEF 2 protein |
| Species | Human |
| Gene ID | 9922 |
| Uniprot | Q6DN90, |
| Species.1 | Mouse |
| Gene ID.1 | 232227 |
| Uniprot.1 | Q8R0S2 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Nucleus . Cell junction, synapse, postsynaptic density . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle . At steady state, may be preferentially cytosolic. |
| Tissue Expression | Expressed in brain, ovary, heart, lung, liver, kidney and leukocytes. Moderate expression was also detected in lung, skeletal muscle, placenta, small intestine, pancreas, spleen and testis. |
| Signaling_pathway | |
| Research Areas | >>Endocytosis |
| Function | Function:In addition to accelerate GTP gamma S binding by ARFs of all three classes, it appears to function preferentially as a guanine nucleotide exchange protein for ARF6, mediating internalisation of beta-1 integrin.,similarity:Belongs to the BRAG family.,similarity:Contains 1 IQ domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 SEC7 domain.,subcellular location:At steady state, may be preferentially cytosolic.,subunit:Interacts with ARF6.,tissue specificity:Expressed in brain, ovary, heart, lung, liver, kidney and leukocytes. Moderate expression was also detected in lung, skeletal muscle, placenta, small intestine, pancreas, spleen and testis., |
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