Price range: $268.00 through $328.00
Background:
This gene encodes a member of the Iroquois homeobox protein family. Homeobox genes in this family are involved in pattern formation in the embryo. The gene product has been identified as a tumor suppressor in gastric (PMID: 21602894, 20440264) and head and neck cancers (PMID: 18559491). A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Dec 2011],
| Size | 50μL/100μL |
| Target | IRX1 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 47kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human IRX1. AA range:221-270 |
| Specificity | IRX1 Polyclonal Antibody detects endogenous levels of IRX1 protein. |
| Gene Name | IRX1 |
| Protein Name | Iroquois-class homeodomain protein IRX-1 |
| Other Name | IRX1; / IRXA1; / Iroquois-class homeodomain protein IRX-1; / Homeodomain protein IRXA1; / Iroquois homeobox protein 1 |
| Species | Human |
| Gene ID | 79192 |
| Uniprot | P78414, |
| Species.1 | Mouse |
| Gene ID.1 | 16371 |
| Uniprot.1 | P81068 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Brain,Lung, |
| Signaling_pathway | |
| Research Areas | |
| Function | similarity:Belongs to the TALE/IRO homeobox family.,similarity:Contains 1 homeobox DNA-binding domain., |
