Price range: $268.00 through $328.00
Background:
IRX3 is a member of the Iroquois homeobox gene family (see IRX1; MIM 606197) and plays a role in an early step of neural development (Bellefroid et al., 1998 [PubMed 9427753]). Members of this family appear to play multiple roles during pattern formation of vertebrate embryos (Lewis et al., 1999 [PubMed 10370142]).[supplied by OMIM, Aug 2009],
| Size | 50μL/100μL |
| Target | IRX3 |
| Reactivity | Human, Mouse |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | 52kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human IRX3. AA range:271-320 |
| Specificity | IRX3 Polyclonal Antibody detects endogenous levels of IRX3 protein. |
| Gene Name | IRX3 |
| Protein Name | Iroquois-class homeodomain protein IRX-3 |
| Other Name | IRX3; / IRXB1; / Iroquois-class homeodomain protein IRX-3; / Homeodomain protein IRXB1; / Iroquois homeobox protein 3 |
| Species | Human |
| Gene ID | 79191 |
| Uniprot | P78415, |
| Species.1 | Mouse |
| Gene ID.1 | 16373 |
| Uniprot.1 | P81067 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Muscle,Skin, |
| Signaling_pathway | |
| Research Areas | |
| Function | similarity:Belongs to the TALE/IRO homeobox family.,similarity:Contains 1 homeobox DNA-binding domain., |
