Name: ITA9 Polyclonal Antibody
SKU: WP0663
Price: 268 USD
Availability: InStock

ITA9 Polyclonal Antibody

Ucallm_WP0663-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP0663-100

Enter the quantity you would like, or drag the panel to find the quantity and price that best for you

Bulk Quote Authorize OEM & ODM

Product details

Background:

integrin subunit alpha 9(ITGA9) Homo sapiens This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers. [provided by RefSeq, Jul 2008],

Specifications

Size	50μL/100μL
Target	ITA9
Reactivity	Human, Mouse
Applications	WB, ELISA
MW(Calculated)
MW(Observed)	113kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-2000; ELISA 1:5000-20000
Formulation	Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human protein . at AA range: 40-120
Specificity	ITA9 Polyclonal Antibody detects endogenous levels of protein.
Gene Name	ITGA9
Protein Name	Integrin alpha-9 (Integrin alpha-RLC)
Other Name
Species	Human
Gene ID	3680
Uniprot	Q13797
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Membrane; Single-pass type I membrane protein .
Tissue Expression	In airway epithelium, in the basal layer of squamous epithelium, and in smooth muscle, skeletal muscle, and hepatocytes. Abundantly expressed in fetal lung and lung cancers.
Signaling_pathway	Cellular Processes >> Cellular community - eukaryotes >> Focal adhesion;Cellular Processes >> Cell motility >> Regulation of actin cytoskeleton;Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway;Environmental Information Processing >> Signaling molecules and interaction >> ECM-receptor interaction;Environmental Information Processing >> Signaling molecules and interaction >> Cell adhesion molecules
Research Areas	>>PI3K-Akt signaling pathway; / >>Focal adhesion; / >>ECM-receptor interaction; / >>Cell adhesion molecules; / >>Regulation of actin cytoskeleton; / >>Human papillomavirus infection; / >>Hypertrophic cardiomyopathy; / >>Arrhythmogenic right ventricular cardiomyopathy; / >>Dilated cardiomyopathy
Function	Function:Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin.,induction:Up-regulated in small cell lung cancers (SCLC).,similarity:Belongs to the integrin alpha chain family.,similarity:Contains 7 FG-GAP repeats.,subunit:Heterodimer of an alpha and a beta subunit. Alpha-9 associates with beta-1.,tissue specificity:In airway epithelium, in the basal layer of squamous epithelium, and in smooth muscle, skeletal muscle, and hepatocytes. Abundantly expressed in fetal lung and lung cancers.,