Product details
Background:
Background:
| Size | 50μL/100μL |
| Target | ITPR3 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 294kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ITPR3 |
| Specificity | This antibody detects endogenous levels of ITPR3 at Human, Mouse,Rat |
| Gene Name | ITPR3 |
| Protein Name | ITPR3 |
| Other Name | Inositol 1,4,5-trisphosphate receptor type 3; / IP3 receptor isoform 3; / IP3R 3; / InsP3R3; / Type 3 inositol 1,4,5-trisphosphate receptor; / Type 3 InsP3 receptor |
| Species | Human |
| Gene ID | 3710 |
| Uniprot | Q14573, |
| Species.1 | Mouse |
| Gene ID.1 | 16440 |
| Uniprot.1 | P70227, |
| Species.2 | Rat |
| Gene ID.2 | 25679 |
| Uniprot.2 | Q63269 |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein. |
| Tissue Expression | Expressed in intestinal crypt and villus epithelial cells. |
| Signaling_pathway | Cellular Processes >> Cell growth and death >> Apoptosis;Cellular Processes >> Cell growth and death >> Cellular senescence;Cellular Processes >> Cellular community - eukaryotes >> Gap junction;Organismal Systems >> Immune system >> Platelet activation;Organismal Systems >> Immune system >> NOD-like receptor signaling pathway;Organismal Systems >> Endocrine system >> Insulin secretion;Organismal Systems >> Endocrine system >> Glucagon signaling pathway;Organismal Systems >> Endocrine system >> GnRH signaling pathway;Organismal Systems >> Endocrine system >> Estrogen signaling pathway;Organismal Systems >> Endocrine system >> Oxytocin signaling pathway;Organismal Systems >> Endocrine system >> Growth hormone synthesis, secretion and action;Organismal Systems >> Endocrine system >> Aldosterone synthesis and secretion;Organismal Systems >> Circulatory system >> Vascular smooth muscle contraction;Organismal Systems >> Nervous system >> Glutamatergic synapse;Organismal Systems >> Nervous system >> Cholinergic synapse;Organismal Systems >> Nervous system >> Dopaminergic synapse;Organismal Systems >> Sensory system >> Inflammatory mediator regulation of TRP channels;Organismal Systems >> Development and regeneration >> Osteoclast differentiation;Human Diseases >> Neurodegenerative disease >> Alzheimer disease;Human Diseases >> Neurodegenerative disease >> Parkinson disease;Human Diseases >> Neurodegenerative disease >> Amyotrophic lateral sclerosis;Human Diseases >> Neurodegenerative disease >> Spinocerebellar ataxia;Human Diseases >> Neurodegenerative disease >> Prion disease;Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases;Environmental Information Processing >> Signal transduction >> Apelin signaling pathway;Environmental Information Processing >> Signal transduction >> Calcium signaling pathway;Environmental Information Processing >> Signal transduction >> cGMP-PKG signaling pathway |
| Research Areas | >>Calcium signaling pathway; / >>cGMP-PKG signaling pathway; / >>Phosphatidylinositol signaling system; / >>Oocyte meiosis; / >>Apoptosis; / >>Cellular senescence; / >>Vascular smooth muscle contraction; / >>Apelin signaling pathway; / >>Gap junction; / >>Platelet activation; / >>NOD-like receptor signaling pathway; / >>C-type lectin receptor signaling pathway; / >>Circadian entrainment; / >>Long-term potentiation; / >>Retrograde endocannabinoid signaling; / >>Glutamatergic synapse; / >>Cholinergic synapse; / >>Serotonergic synapse; / >>Dopaminergic synapse; / >>Long-term depression; / >>Taste transduction; / >>Inflammatory mediator regulation of TRP channels; / >>Insulin secretion; / >>GnRH signaling pathway; / >>Estrogen signaling pathway; / >>Thyroid hormone synthesis; / >>Oxytocin signaling pathway; / >>Glucagon signaling pathway; / >>Renin secretion; / >>Aldosterone synthesis and secretion; / >>Cortisol synthesis and secretion; / >>Parathyroid hormone synthesis, secretion and action; / >>GnRH secretion; / >>Cushing syndrome; / >>Growth hormone synthesis, secretion and action; / >>Salivary secretion; / >>Gastric acid secretion; / >>Pancreatic secretion; / >>Alzheimer disease; / >>Parkinson disease; / >>Amyotrophic lateral sclerosis; / >>Spinocerebellar ataxia; / >>Prion disease; / >>Pathways of neurodegeneration - multiple diseases; / >>Shigellosis; / >>Human cytomegalovirus infection; / >>Kaposi sarcoma-associated herpesvirus infection; / >>Human immunodeficiency virus 1 infection; / >>Proteoglycans in cancer |
| Function |