JTV1 rabbit pAb
Ucallm_WP6035-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | AIMP2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 35kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human JTV1 |
| Specificity | This antibody detects endogenous levels of JTV1 at Human, Mouse,Rat |
| Gene Name | AIMP2 JTV1 PRO0992 |
| Protein Name | Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (Multisynthase complex auxiliary component p38) (Protein JTV-1) |
| Other Name | |
| Species | Human |
| Gene ID | 7965 |
| Uniprot | Q13155, |
| Species.1 | Mouse |
| Gene ID.1 | 231872 |
| Uniprot.1 | Q8R010, |
| Species.2 | Rat |
| Gene ID.2 | 288480 |
| Uniprot.2 | Q32PX2 |
| Cellular Localization | Cytoplasm, cytosol . Nucleus . Following DNA damage, dissociates from the aminoacyl-tRNA synthase complex and translocates from the cytoplasm to the nucleus. . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Required for assembly and stability of the aminoacyl-tRNA synthase complex . Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor. |
Please login to post questions
Related products
