KDSR rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | KDSR |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 37kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human KDSR |
| Specificity | This antibody detects endogenous levels of KDSR at Human, Mouse |
| Gene Name | KDSR FVT1 |
| Protein Name | 3-ketodihydrosphingosine reductase (KDS reductase) (3-dehydrosphinganine reductase) (Follicular variant translocation protein 1) (FVT-1) |
| Other Name | |
| Species | Human |
| Gene ID | 2531 |
| Uniprot | Q06136, |
| Species.1 | Mouse |
| Gene ID.1 | 70750 |
| Uniprot.1 | Q6GV12 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein . |
| Tissue Expression | Expressed in all tissues examined. Highest expression in placenta. High expression in lung, kidney, stomach and small intestine, low expression in heart, spleen and skeletal muscle. Weakly expressed in normal hematopoietic tissues. Higher expression in some T-cell malignancies and PHA-stimulated lymphocytes. |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS). |
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