SKU: WP0452 Categories: ,

KIF1C Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP0452-100
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Product details

Background:

kinesin family member 1C(KIF1C) Homo sapiens The protein encoded by this gene is a member of the kinesin-like protein family. The family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. Mutations in this gene are a cause of spastic ataxia 2, autosomal recessive. [provided by RefSeq, May 2014],

Specifications

Size50μL/100μL
TargetKIF1C
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)121kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 1110-1190
SpecificityKIF1C Polyclonal Antibody detects endogenous levels of protein.
Gene NameKIF1C KIAA0706
Protein NameKinesin-like protein KIF1C
Other Name
SpeciesHuman
Gene ID10749
UniprotO43896,
Species.1Mouse
Gene ID.116562
Uniprot.1O35071,
Species.2Rat
Gene ID.2113886
Uniprot.2O35787
Cellular LocalizationCytoplasm, cytoskeleton .
Tissue ExpressionExpressed in all tissues examined, with most abundant expression in heart and skeletal muscle.
Signaling_pathway
Research Areas
FunctionFunction:Motor required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum. Has a microtubule plus end-directed motility.,PTM:Phosphorylated on tyrosine residues.,similarity:Belongs to the kinesin-like protein family. Unc-104 subfamily.,similarity:Contains 1 FHA domain.,similarity:Contains 1 kinesin-motor domain.,subunit:Monomer .,tissue specificity:Expressed in all tissues examined, with most abundant expression in heart and skeletal muscle.,
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