KLK10 rabbit pAb
Ucallm_WP4189-50
Price range: $268.00 through $328.00
Product details
Background:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | KLK10 |
| Reactivity | Human, Rat |
| Applications | WB |
| MW(Calculated) | 30kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human KLK10 AA range: 199-249 |
| Specificity | This antibody detects endogenous levels of KLK10 at Human/Rat |
| Gene Name | KLK10 NES1 PRSSL1 |
| Protein Name | KLK10 |
| Other Name | |
| Species | Human |
| Gene ID | 5655 |
| Uniprot | O43240, |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | Rat |
| Gene ID.2 | 100911689 |
| Uniprot.2 | P36375 |
| Cellular Localization | Secreted . |
| Tissue Expression | Expressed in breast, ovary and prostate. |
| Signaling_pathway | |
| Research Areas | |
| Function | developmental stage:Down-regulated during breast cancer progression.,Function:Has a tumor-suppressor role for NES1 in breast and prostate cancer.,similarity:Belongs to the peptidase S1 family.,similarity:Belongs to the peptidase S1 family. Kallikrein subfamily.,similarity:Contains 1 peptidase S1 domain.,tissue specificity:Expressed in breast, ovary and prostate., |
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