Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human KLRG1
Specificity
This antibody detects endogenous levels of KLRG1 at Human, Mouse,Rat
Gene Name
KLRG1 CLEC15A MAFA MAFAL
Protein Name
Killer cell lectin-like receptor subfamily G member 1 (C-type lectin domain family 15 member A) (ITIM-containing receptor MAFA-L) (MAFA-like receptor) (Mast cell function-associated antigen)
Other Name
Species
Human
Gene ID
10219
Uniprot
Q96E93,
Species.1
Mouse
Gene ID.1
50928
Uniprot.1
O88713,
Species.2
Rat
Gene ID.2
58975
Uniprot.2
Q64335
Cellular Localization
Cell membrane; Single-pass type II membrane protein .
Tissue Expression
Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells.
Signaling_pathway
Research Areas
Function
Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.