SKU: WP17016 Categories: ,

KR131 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP17016-100
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Product details

Background:

Hair keratins and hair keratin-associated proteins (KAPs), such as KRTAP13-1, are the main structural proteins of hair fibers (Rogers et al., 2002 [PubMed 12359730]).[supplied by OMIM, Mar 2008],

Specifications

Size50μL/100μL
TargetKR131
ReactivityHuman
ApplicationsWB, ELISA, IHC
MW(Calculated)19kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human KR131 AA range: 99-149
SpecificityThis antibody detects endogenous levels of KR131 at Human
Gene NameKRTAP13-1 KAP13.1 KRTAP13.1
Protein NameKR131
Other Name
SpeciesHuman
Gene ID140258
UniprotQ8IUC0
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localizationintermediate filament,
Tissue ExpressionWeak expression seen in the late matrix and entire cortex area of the hair follicle.
Signaling_pathway
Research Areas
FunctionCaution:The sequence of 1-41 of PubMed:12359730 has not been submitted.,Function:In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.,similarity:Belongs to the PMG family.,subunit:Interacts with hair keratins.,tissue specificity:Weak expression seen in the late matrix and entire cortex area of the hair follicle.,
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