SKU: WP7860 Categories: ,

TPBG rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7860-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetTPBG
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)46kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human TPBG
SpecificityThis antibody detects endogenous levels of TPBG at Human, Mouse,Rat
Gene NameTPBG 5T4
Protein NameTrophoblast glycoprotein (5T4 oncofetal antigen) (5T4 oncofetal trophoblast glycoprotein) (5T4 oncotrophoblast glycoprotein) (M6P1)
Other Name
SpeciesHuman
Gene ID7162
UniprotQ13641,
Species.1Mouse
Gene ID.121983
Uniprot.1Q9Z0L0,
Species.2Rat
Gene ID.283684
Uniprot.2Q5PQV5
Cellular LocalizationCell membrane; Single-pass type I membrane protein .
Tissue ExpressionExpressed by all types of trophoblasts as early as 9 weeks of development. Specific for trophoblastic cells except for amniotic epithelium. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.
Signaling_pathway
Research Areas
FunctionMay function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization.
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