TPBG rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | TPBG |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 46kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TPBG |
| Specificity | This antibody detects endogenous levels of TPBG at Human, Mouse,Rat |
| Gene Name | TPBG 5T4 |
| Protein Name | Trophoblast glycoprotein (5T4 oncofetal antigen) (5T4 oncofetal trophoblast glycoprotein) (5T4 oncotrophoblast glycoprotein) (M6P1) |
| Other Name | |
| Species | Human |
| Gene ID | 7162 |
| Uniprot | Q13641, |
| Species.1 | Mouse |
| Gene ID.1 | 21983 |
| Uniprot.1 | Q9Z0L0, |
| Species.2 | Rat |
| Gene ID.2 | 83684 |
| Uniprot.2 | Q5PQV5 |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein . |
| Tissue Expression | Expressed by all types of trophoblasts as early as 9 weeks of development. Specific for trophoblastic cells except for amniotic epithelium. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma. |
| Signaling_pathway | |
| Research Areas | |
| Function | May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. |
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