IHC 1:50-200; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human KR191 AA range: 36-86
Specificity
This antibody detects endogenous levels of KR191 at Human
Gene Name
KRTAP19-1 KAP19.1 KRTAP19.1
Protein Name
KR191
Other Name
Species
Human
Gene ID
337882
Uniprot
Q8IUB9
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
intermediate filament,
Tissue Expression
Detected in the upper portion of the hair cortex.
Signaling_pathway
Research Areas
Function
Function:In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.,similarity:Belongs to the KRTAP type 19 family.,subunit:Interacts with hair keratins.,tissue specificity:Detected in the upper portion of the hair cortex.,