SKU: WP3996 Categories: ,

KRA94 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP3996-100
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Product details

Background:

This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the ultrahigh sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetKRA94
ReactivityHuman
ApplicationsWB
MW(Calculated)17kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human KRA94 AA range: 48-98
SpecificityThis antibody detects endogenous levels of KRA94 at Human
Gene NameKRTAP9-4 KAP9.4 KRTAP9.4
Protein NameKRA94
Other Name
SpeciesHuman
Gene ID85280
UniprotQ9BYQ2
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localizationkeratin filament,
Tissue Expression
Signaling_pathway
Research Areas
FunctionFunction:In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.,similarity:Belongs to the KRTAP type 9 family.,subunit:Interacts with hair keratins.,
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