Name: L-type Ca++ CP γ1 Polyclonal Antibody
SKU: WP13031
Price: 268 USD
Availability: InStock

L-type Ca++ CP γ1 Polyclonal Antibody

Ucallm_WP13031-50

Price range: $268.00 through $328.00

Size

100μl

50μl

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SKU: WP13031-100

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Product details

Background:

calcium voltage-gated channel auxiliary subunit gamma 1(CACNG1) Homo sapiens Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is part of skeletal muscle 1, 4-dihydropyridine-sensitive calcium channels and is an integral membrane protein that plays a role in excitation-contraction coupling. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs). [provided by RefSeq, Dec 2010],

Specifications

Size	50μL/100μL
Target	L-type Ca++ CP γ1
Reactivity	Human, Mouse, Rat
Applications	WB, ELISA
MW(Calculated)
MW(Observed)	25kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; ELISA 1:5000; Not yet tested in other applications.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human CACNG1. AA range:137-186
Specificity	L-type Ca++ CP γ1 Polyclonal Antibody detects endogenous levels of L-type Ca++ CP γ1 protein.
Gene Name	CACNG1
Protein Name	Voltage-dependent calcium channel gamma-1 subunit
Other Name	CACNG1; / CACNLG; / Voltage-dependent calcium channel gamma-1 subunit; / Dihydropyridine-sensitive L-type; / skeletal muscle calcium channel subunit gamma
Species	Human
Gene ID	786
Uniprot	Q06432,
Species.1	Mouse
Gene ID.1	12299
Uniprot.1	O70578,
Species.2	Rat
Gene ID.2	29658
Uniprot.2	P97707
Cellular Localization	Cell membrane, sarcolemma; Multi-pass membrane protein .
Tissue Expression	Skeletal muscle.
Signaling_pathway	Organismal Systems >> Endocrine system >> Oxytocin signaling pathway;Organismal Systems >> Circulatory system >> Cardiac muscle contraction;Organismal Systems >> Circulatory system >> Adrenergic signaling in cardiomyocytes;Environmental Information Processing >> Signal transduction >> MAPK signaling pathway
Research Areas	>>MAPK signaling pathway; / >>Cardiac muscle contraction; / >>Adrenergic signaling in cardiomyocytes; / >>Oxytocin signaling pathway; / >>Hypertrophic cardiomyopathy; / >>Arrhythmogenic right ventricular cardiomyopathy; / >>Dilated cardiomyopathy
Function	Function:This protein is a subunit of the dihydropyridine (DHP) sensitive calcium channel. Plays a role in excitation-contraction coupling. The skeletal muscle DHP-sensitive Ca(2+) channel may function only as a multiple subunit complex.,similarity:Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.,subunit:The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma.,tissue specificity:Skeletal muscle.,

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L-type Ca++ CP γ1 Polyclonal Antibody

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L-type Ca++ CP γ1 Polyclonal Antibody

Product details

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