Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human LAMP5 AA range: 143-193
Specificity
This antibody detects endogenous levels of LAMP5 at Human/Mouse/Rat
Gene Name
LAMP5 C20orf103
Protein Name
LAMP5
Other Name
Species
Human
Gene ID
24141
Uniprot
Q9UJQ1,
Species.1
Mouse
Gene ID.1
76161
Uniprot.1
Q9D387,
Species.2
Rat
Gene ID.2
362220
Uniprot.2
Q5PPI4
Cellular Localization
Cell membrane; Single-pass type I membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type I membrane protein . Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein . Endosome membrane; Single-pass type I membrane protein . Cytoplasmic vesicle membrane; Single-pass type I membrane protein . Cell projection, dendrite . Cell projection, growth cone membrane; Single-pass type I membrane protein . Early endosome membrane; Single-pass type I membrane protein . Recycling endosome . Recycles from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane (By similarity). Colocalizes with UNC93B1 in large endosomal intracellular vesicles (PubMed:21642595). Accumulates in the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) before its disappearance upon activation by CpG dinucleotides (PubMed:21642595). Associates with cortical membranes (PubMed:21642595). Localizes mostly in cytoplasmic vesicles of neuronal cell body (By similarity). Localizes to synaptic vesicles in a subset of GABAergic neurons (By similarity). .
Tissue Expression
Expressed in plasmocytoid dendritic cells. Expressed in suprabasal skin keratinocytes and squamous cells (at protein level). Expressed in the brain and weakly in spleen and skin. Expressed in plasmocytoid dendritic cells.