SKU: WP7990 Categories: ,

LEPROT rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7990-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetLEPROT
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)14kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human LEPROT
SpecificityThis antibody detects endogenous levels of LEPROT at Human, Mouse,Rat
Gene NameLEPROT LEPR OBR
Protein NameLeptin receptor gene-related protein (Leptin receptor overlapping transcript protein) (OB-R gene-related protein) (OB-RGRP)
Other Name
SpeciesHuman
Gene ID54741
UniprotO15243,
Species.1Mouse
Gene ID.1230514
Uniprot.1O89013,
Species.2Rat
Gene ID.256766
Uniprot.2Q9JLS8
Cellular LocalizationGolgi apparatus membrane; Multi-pass membrane protein . Endosome membrane .
Tissue ExpressionExpressed at the highest levels in heart and placenta and at a lesser extent in lung, liver, skeletal muscle, kidney and pancreas.
Signaling_pathway
Research Areas
FunctionNegatively regulates leptin receptor (LEPR) cell surface expression, and thus decreases response to leptin. Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability.
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