SKU: WP1244 Categories: ,

LHX8 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP1244-100
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Product details

Background:

The protein encoded by this gene is a member of the LIM homeobox family of proteins, which are involved in patterning and differentiation of various tissue types. These proteins contain two tandemly repeated cysteine-rich double-zinc finger motifs known as LIM domains, in addition to a DNA-binding homeodomain. This family member is a transcription factor that plays a role in tooth morphogenesis. It is also involved in oogenesis and in neuronal differentiation. This gene is a candidate gene for cleft palate, and it is also associated with odontoma formation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012],

Specifications

Size50μL/100μL
TargetLHX8
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)39kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 150-230
SpecificityLHX8 Polyclonal Antibody detects endogenous levels of protein.
Gene NameLHX8
Protein NameLIM/homeobox protein Lhx8 (LIM homeobox protein 8)
Other Name
SpeciesHuman
Gene ID431707
UniprotQ68G74,
Species.1Mouse
Gene ID.1
Uniprot.1O35652
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus .
Tissue ExpressionPeripheral blood,Testis,
Signaling_pathway
Research Areas
FunctionFunction:Transcription factor involved in differentiation of certain neurons and mesenchymal cells.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 LIM zinc-binding domain.,similarity:Contains 2 LIM zinc-binding domains.,
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