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Home/Reagents/Antibody/Primary antibody/Polyclonal Antibody/Rabbit pAb/LRIG1 Polyclonal Antibody
SKU: WP3276 Categories: ,

LRIG1 Polyclonal Antibody

Ucallm_WP3276-50

Price range: $268.00 through $328.00

SKU: WP3276-100
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Product details

Background:

domain:The LRRs and the Ig-domains are each sufficient for EGFR/ERBB1 binding. This interaction is abolished only when these two domains are deleted., function:Act as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation., induction:By EGF., similarity:Contains 17 LRR (leucine-rich) repeats., similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains., subunit:Interacts with EGFR/ERBB1, ERBB2, ERBB3 and ERBB4., tissue specificity:Widely expressed.,

Specifications

Size50μL/100μL
TargetLRIG1
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)120kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein
SpecificityLRIG1 Polyclonal Antibody detects endogenous levels of protein.
Gene NameLRIG1 LIG1
Protein NameLeucine-rich repeats and immunoglobulin-like domains protein 1 (LIG-1)
Other Name
SpeciesHuman
Gene ID26018
UniprotQ96JA1,
Species.1Mouse
Gene ID.1
Uniprot.1P70193
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCell membrane; Single-pass type I membrane protein .
Tissue ExpressionWidely expressed.
Signaling_pathway
Research Areas
FunctionDomain:The LRRs and the Ig-domains are each sufficient for EGFR/ERBB1 binding. This interaction is abolished only when these two domains are deleted.,Function:Act as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.,induction:By EGF.,similarity:Contains 17 LRR (leucine-rich) repeats.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with EGFR/ERBB1, ERBB2, ERBB3 and ERBB4.,tissue specificity:Widely expressed.,
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