Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human LSG1
Specificity
This antibody detects endogenous levels of LSG1 at Human, Mouse,Rat
Gene Name
LSG1
Protein Name
Large subunit GTPase 1 homolog (hLsg1) (EC 3.6.1.-)
Other Name
Species
Human
Gene ID
55341
Uniprot
Q9H089,
Species.1
Mouse
Gene ID.1
224092
Uniprot.1
Q3UM18,
Species.2
Rat
Gene ID.2
288029
Uniprot.2
Q5BJT6
Cellular Localization
Cytoplasm . Endoplasmic reticulum . Nucleus, Cajal body . Shuttles between the Cajal bodies in the nucleus and the endoplasmic reticulum.
Tissue Expression
Signaling_pathway
Research Areas
Function
GTPase required for the XPO1/CRM1-mediated nuclear export of the 60S ribosomal subunit. Probably acts by mediating the release of NMD3 from the 60S ribosomal subunit after export into the cytoplasm (Probable).