Product details
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LSS rabbit pAb
Ucallm_WP6221-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | LSS |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 81kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human LSS |
| Specificity | This antibody detects endogenous levels of LSS at Human, Mouse,Rat |
| Gene Name | LSS OSC |
| Protein Name | Lanosterol synthase (2,3-epoxysqualene--lanosterol cyclase) (Oxidosqualene--lanosterol cyclase) (OSC) (hOSC) |
| Other Name | |
| Species | Human |
| Gene ID | 4047 |
| Uniprot | P48449, |
| Species.1 | Mouse |
| Gene ID.1 | 16987 |
| Uniprot.1 | Q8BLN5, |
| Species.2 | Rat |
| Gene ID.2 | 81681 |
| Uniprot.2 | P48450 |
| Cellular Localization | Endoplasmic reticulum membrane; Peripheral membrane protein . |
| Tissue Expression | Widely expressed. Expressed in the hair bulb, the outer root sheath and hair matrix of the hair follicle epithelium. Also detected in dermal papilla, epidermis, sweat glands, sebaceous glands, and blood vessels. |
| Signaling_pathway | |
| Research Areas | |
| Function | Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus . Through the production of lanosterol may regulate lens protein aggregation and increase transparency . |
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