Price range: $268.00 through $328.00
Background:
This gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | Maf1 |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | 29kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from Maf1 . at AA range: 110-190 |
| Specificity | Maf1 Polyclonal Antibody detects endogenous levels of Maf1 protein. |
| Gene Name | MAF1 |
| Protein Name | Repressor of RNA polymerase III transcription MAF1 homolog |
| Other Name | MAF1; / Repressor of RNA polymerase III transcription MAF1 homolog |
| Species | Human |
| Gene ID | 84232 |
| Uniprot | Q9H063, |
| Species.1 | Mouse |
| Gene ID.1 | 68877 |
| Uniprot.1 | Q9D0U6, |
| Species.2 | Rat |
| Gene ID.2 | 315093 |
| Uniprot.2 | Q5XIH0 |
| Cellular Localization | Nucleus . Cytoplasm . |
| Tissue Expression | Brain,Epithelium,Lung,Uterus, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Mediator of diverse signals that repress RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.,similarity:Belongs to the MAF1 family.,subunit:Interacts with BRF2., |
