Product details
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MAGT1 rabbit pAb
Ucallm_WP6082-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | MAGT1 |
| Reactivity | Human, Rat |
| Applications | WB |
| MW(Calculated) | 37kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human MAGT1 |
| Specificity | This antibody detects endogenous levels of MAGT1 at Human,Rat |
| Gene Name | MAGT1 IAG2 PSEC0084 UNQ628/PRO1244 |
| Protein Name | Magnesium transporter protein 1 (MagT1) (Implantation-associated protein) (IAP) |
| Other Name | |
| Species | Human |
| Gene ID | 84061 |
| Uniprot | Q9H0U3, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9CQY5, |
| Species.2 | Rat |
| Gene ID.2 | 116967 |
| Uniprot.2 | O35777 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . Endoplasmic reticulum . Endoplasmic reticulum membrane; Multi-pass membrane protein . |
| Tissue Expression | Ubiquitous. Expressed at very low levels in brain, lung and kidney. |
| Signaling_pathway | Genetic Information Processing >> Folding, sorting and degradation >> Protein processing in endoplasmic reticulum |
| Research Areas | |
| Function | Accessory component of the STT3B-containing form of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains . Involved in N-glycosylation of STT3B-dependent substrates . Specifically required for the glycosylation of a subset of acceptor sites that are near cysteine residues; in this function seems to act redundantly with TUSC3. In its oxidized form proposed to form transient mixed disulfides with a glycoprotein substrate to facilitate access of STT3B to the unmodified acceptor site. Has also oxidoreductase-independent functions in the STT3B-containing OST complex possibly involving substrate recognition.; May be involved in Mg(2+) transport in epithelial cells. |
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