MAL Polyclonal Antibody
Ucallm_WP1313-50
Price range: $268.00 through $328.00
Product details
Background:
The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3. [provided by RefSeq, May 2012],
Specifications
| Size | 50μL/100μL |
| Target | MAL |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 16kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 70-150 |
| Specificity | MAL Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | MAL |
| Protein Name | Myelin and lymphocyte protein (T-lymphocyte maturation-associated protein) |
| Other Name | |
| Species | Human |
| Gene ID | 4118 |
| Uniprot | P21145, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | O09198, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q64349 |
| Cellular Localization | Membrane; Multi-pass membrane protein. |
| Tissue Expression | Brain,Lung,Lymphocyte,Placenta, |
| Signaling_pathway | |
| Research Areas | |
| Function | developmental stage:Expressed in the intermediate and late stages of T-cell differentiation.,Function:Could be an important component in vesicular trafficking cycling between the Golgi complex and the apical plasma membrane. Could be involved in myelin biogenesis and/or myelin function.,PTM:Lipoprotein.,similarity:Belongs to the MAL family.,similarity:Contains 1 MARVEL domain., |
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