Product details
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MAP1S rabbit pAb
Ucallm_WP6373-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | MAP1S |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 116kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human MAP1S |
| Specificity | This antibody detects endogenous levels of MAP1S at Human, Mouse,Rat |
| Gene Name | MAP1S BPY2IP1 C19orf5 MAP8 VCY2IP1 |
| Protein Name | Microtubule-associated protein 1S (MAP-1S) (BPY2-interacting protein 1) (Microtubule-associated protein 8) (Variable charge Y chromosome 2-interacting protein 1) (VCY2-interacting protein 1) (VCY2IP-1) [Cleaved into: MAP1S heavy chain; MAP1S light chain] |
| Other Name | |
| Species | Human |
| Gene ID | 55201 |
| Uniprot | Q66K74, |
| Species.1 | Mouse |
| Gene ID.1 | 270058 |
| Uniprot.1 | Q8C052, |
| Species.2 | Rat |
| Gene ID.2 | 290640 |
| Uniprot.2 | P0C5W1 |
| Cellular Localization | Nucleus. Cytoplasm, cytosol. Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, spindle . Detected in filopodia-like protrusions and synapses (By similarity). Detected in perinuclear punctate network corresponding to mitochondrial aggregates and in the nucleus in cells exhibiting apoptosis. Associated specifically with microtubules stabilized by paclitaxel and colocalizes with RASSF1 isoform A. In interphase cells, shows a diffuse cytoplasmic staining with partial localization to the microtubules. During the different stages of mitosis detected at the spindle microtubules. . |
| Tissue Expression | Expressed in neurons (at protein level). Expressed in spermatocytes, spermatids and spermatozoa. Expressed in the cerebral cortex. Highly expressed in testis. Moderately expressed in the brain, colon, heart, kidney, liver, lung, placenta, small intestine, spleen and stomach. Weakly expressed in muscle. |
| Signaling_pathway | |
| Research Areas | |
| Function | Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles (By similarity). |
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