Product details
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MATE 2 rabbit pAb
Ucallm_WP8219-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | SLC47A2 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 66kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human MATE 2 |
| Specificity | This antibody detects endogenous levels of MATE 2 at Human, Mouse |
| Gene Name | SLC47A2 MATE2 |
| Protein Name | Multidrug and toxin extrusion protein 2 (MATE-2) (hMATE-2) (Kidney-specific H(+)/organic cation antiporter) (Solute carrier family 47 member 2) |
| Other Name | |
| Species | Human |
| Gene ID | 146802 |
| Uniprot | Q86VL8, |
| Species.1 | Mouse |
| Gene ID.1 | 380701 |
| Uniprot.1 | Q3V050 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . Localized at the brush border membranes of the proximal tubules. |
| Tissue Expression | Isoform 3 is predominantly expressed in kidney. Isoform 6 is expressed in brain. |
| Signaling_pathway | |
| Research Areas | |
| Function | Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes. |
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