MBOA7 rabbit pAb
Ucallm_WP4176-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a member of the membrane-bound O-acyltransferases family of integral membrane proteins that have acyltransferase activity. The encoded protein is a lysophosphatidylinositol acyltransferase that has specificity for arachidonoyl-CoA as an acyl donor. This protein is involved in the reacylation of phospholipids as part of the phospholipid remodeling pathway known as the Land cycle. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009],
Specifications
| Size | 50μL/100μL |
| Target | MBOA7 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 52kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human MBOA7 AA range: 293-343 |
| Specificity | This antibody detects endogenous levels of MBOA7 at Human/Mouse |
| Gene Name | MBOAT7 BB1 LENG4 OACT7 |
| Protein Name | MBOA7 |
| Other Name | |
| Species | Human |
| Gene ID | 79143 |
| Uniprot | Q96N66, |
| Species.1 | Mouse |
| Gene ID.1 | 77582 |
| Uniprot.1 | Q8CHK3 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein . Localized in specific membrane structures termed mitochondria-associated membranes (MAMs) which connect the endoplasmic reticulum (ER) and the mitochondria. . |
| Tissue Expression | Overexpressed in metastatic breast and bladder carcinomas relative to normal breast epithelium and urothelium. |
| Signaling_pathway | |
| Research Areas | >>Glycerophospholipid metabolism |
| Function | Catalytic activity:Acyl-CoA + 1-acyl-sn-glycero-3-phosphatidylinositol = CoA + 1,2-diacyl-sn-glycero-3-phosphatidylinositol.,enzyme regulation:Activity is inhibited by thimerosal.,Function:Acyltransferase which mediates the conversion of lysophosphatidylinositol (1-acylglycerophosphatidylinositol or LPI) into phosphatidylinositol (1,2-diacyl-sn-glycero-3-phosphoinositol or PI) (LPIAT activity). Prefers arachidonoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.,pathway:Lipid metabolism; phospholipid metabolism.,similarity:Belongs to the membrane-bound acyltransferase family.,tissue specificity:Overexpressed in metastatic breast and bladder carcinomas relative to normal breast epithelium and urothelium., |
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