Name: MELK Polyclonal Antibody
SKU: WP13143
Price: 268 USD
Availability: InStock

MELK Polyclonal Antibody

Ucallm_WP13143-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP13143-100

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Product details

Background:

catalytic activity:ATP + a protein = ADP + a phosphoprotein., function:Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis., PTM:Autophosphorylated. Thr-478 phosphorylation during mitosis promotes interaction with PPP1R8., similarity:Belongs to the protein kinase superfamily., similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily., similarity:Contains 1 KA1 (kinase-associated) domain., similarity:Contains 1 protein kinase domain., subunit:Interacts with ZNF622 and PPP1R8., tissue specificity:Expressed in placenta, kidney, thymus, testis, ovary and intestine.,

Specifications

Size	50μL/100μL
Target	MELK
Reactivity	Human, Mouse
Applications	WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)	75kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human MELK. AA range:431-480
Specificity	MELK Polyclonal Antibody detects endogenous levels of MELK protein.
Gene Name	MELK
Protein Name	Maternal embryonic leucine zipper kinase
Other Name	MELK; / KIAA0175; / Maternal embryonic leucine zipper kinase; / hMELK; / Protein kinase Eg3; / pEg3 kinase; / Protein kinase PK38; / hPK38; / Tyrosine-protein kinase MELK
Species	Human
Gene ID	9833
Uniprot	Q14680,
Species.1	Mouse
Gene ID.1
Uniprot.1	Q61846
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Cell membrane; Peripheral membrane protein .
Tissue Expression	Expressed in placenta, kidney, thymus, testis, ovary and intestine.
Signaling_pathway
Research Areas
Function	Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,Function:Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis.,PTM:Autophosphorylated. Thr-478 phosphorylation during mitosis promotes interaction with PPP1R8.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.,similarity:Contains 1 KA1 (kinase-associated) domain.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with ZNF622 and PPP1R8.,tissue specificity:Expressed in placenta, kidney, thymus, testis, ovary and intestine.,

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MELK Polyclonal Antibody

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MELK Polyclonal Antibody

Product details

Specifications

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