Price range: $268.00 through $328.00
Background:
This gene encodes a 25-kD microfibril-associated glycoprotein which is a component of microfibrils of the extracellular matrix. The encoded protein promotes attachment of cells to microfibrils via alpha-V-beta-3 integrin. Deficiency of this gene in mice results in neutropenia. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],
| Size | 50μL/100μL |
| Target | MFAP5 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 19kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 10-90 |
| Specificity | MFAP5 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | MFAP5 MAGP2 |
| Protein Name | Microfibrillar-associated protein 5 (MFAP-5) (MP25) (Microfibril-associated glycoprotein 2) (MAGP-2) |
| Other Name | |
| Species | Human |
| Gene ID | 8076 |
| Uniprot | Q13361, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9QZJ6 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted, extracellular space, extracellular matrix. |
| Tissue Expression | Liver,Skeletal muscle,Tongue,Uterus, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Component of the elastin-associated microfibrils.,PTM:Forms intermolecular disulfide bonds either with other MAGP-2 molecules or with other components of the microfibrils.,similarity:Belongs to the MFAP family., |
