Name: MGST2 Polyclonal Antibody
SKU: WP13161
Price: 268 USD
Availability: InStock

MGST2 Polyclonal Antibody

Ucallm_WP13161-50

Price range: $268.00 through $328.00

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100μl

50μl

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SKU: WP13161-100

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Product details

Background:

The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, several of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes a protein which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2011],

Specifications

Size	50μL/100μL
Target	MGST2
Reactivity	Human, Mouse
Applications	WB, ELISA, IHC
MW(Calculated)
MW(Observed)	17kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from MGST2 . at AA range: 370-450
Specificity	MGST2 Polyclonal Antibody detects endogenous levels of MGST2 protein.
Gene Name	MGST2
Protein Name	Microsomal glutathione S-transferase 2
Other Name	MGST2; / GST2; / Microsomal glutathione S-transferase 2; / Microsomal GST-2; / Microsomal GST-II
Species	Human
Gene ID	4258
Uniprot	Q99735
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Endoplasmic reticulum membrane; Multi-pass membrane protein . Microsome membrane; Multi-pass membrane protein .
Tissue Expression	Liver, spleen, skeletal muscle, heart, adrenals, pancreas, prostate, testis, fetal liver, and fetal spleen. Very low expression in lung, brain, placenta and bone marrow (PubMed:8703034). Abundantly expressed in human umbilical vein endothelial cells (at protein level) (PubMed:11322876).
Signaling_pathway	Human Diseases >> Cancer: overview >> Pathways in cancer;Human Diseases >> Cancer: specific types >> Hepatocellular carcinoma
Research Areas	>>Glutathione metabolism; / >>Metabolism of xenobiotics by cytochrome P450; / >>Drug metabolism - cytochrome P450; / >>Drug metabolism - other enzymes; / >>Metabolic pathways; / >>Platinum drug resistance; / >>Pathways in cancer; / >>Chemical carcinogenesis - DNA adducts; / >>Chemical carcinogenesis - receptor activation; / >>Chemical carcinogenesis - reactive oxygen species; / >>Hepatocellular carcinoma; / >>Fluid shear stress and atherosclerosis
Function	Catalytic activity:RX + glutathione = HX + R-S-glutathione.,Function:Can catalyze the production of LTC4 from LTA4 and reduced glutathione. Can catalyze the conjugation of 1-chloro-2,4-dinitrobenzene with reduced glutathione.,similarity:Belongs to the MAPEG family.,subunit:Homotrimer.,tissue specificity:Liver, spleen, skeletal muscle, heart, adrenals, pancreas, prostate, testis, fetal liver, and fetal spleen. Very low expression in lung, brain, placenta and bone marrow.,

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MGST2 Polyclonal Antibody

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MGST2 Polyclonal Antibody

Product details

Specifications

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