Mindin Polyclonal Antibody
Product details
Background:
function:Cell adhesion protein that promote adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens., similarity:Contains 1 spondin domain., similarity:Contains 1 TSP type-1 domain., tissue specificity:Expressed in normal lung tissues but not in lung carcinoma cell lines.,
Specifications
| Size | 50μL/100μL |
| Target | Mindin |
| Reactivity | Human, Mouse, Rat, Monkey |
| Applications | WB, IHC |
| MW(Calculated) | |
| MW(Observed) | 37kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-300 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SPON2. AA range:71-120 |
| Specificity | Mindin Polyclonal Antibody detects endogenous levels of Mindin protein. |
| Gene Name | SPON2 |
| Protein Name | Spondin-2 |
| Other Name | SPON2; / DIL1; / Spondin-2; / Differentially expressed in cancerous and non-cancerous lung cells 1; / DIL-1; / Mindin |
| Species | Human |
| Gene ID | 10417 |
| Uniprot | Q9BUD6, |
| Species.1 | Mouse |
| Gene ID.1 | 100689 |
| Uniprot.1 | Q8BMS2, |
| Species.2 | Rat |
| Gene ID.2 | 171569 |
| Uniprot.2 | Q9WV75 |
| Cellular Localization | Secreted, extracellular space, extracellular matrix . |
| Tissue Expression | Expressed in normal lung tissue but not in lung carcinoma cell lines. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Cell adhesion protein that promote adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens.,similarity:Contains 1 spondin domain.,similarity:Contains 1 TSP type-1 domain.,tissue specificity:Expressed in normal lung tissues but not in lung carcinoma cell lines., |
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