SKU: WP13170 Categories: ,

Mindin Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP13170-100
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Product details

Background:

function:Cell adhesion protein that promote adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens., similarity:Contains 1 spondin domain., similarity:Contains 1 TSP type-1 domain., tissue specificity:Expressed in normal lung tissues but not in lung carcinoma cell lines.,

Specifications

Size50μL/100μL
TargetMindin
ReactivityHuman, Mouse, Rat, Monkey
ApplicationsWB, IHC
MW(Calculated)
MW(Observed)37kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; IHC 1:50-300 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human SPON2. AA range:71-120
SpecificityMindin Polyclonal Antibody detects endogenous levels of Mindin protein.
Gene NameSPON2
Protein NameSpondin-2
Other NameSPON2; / DIL1; / Spondin-2; / Differentially expressed in cancerous and non-cancerous lung cells 1; / DIL-1; / Mindin
SpeciesHuman
Gene ID10417
UniprotQ9BUD6,
Species.1Mouse
Gene ID.1100689
Uniprot.1Q8BMS2,
Species.2Rat
Gene ID.2171569
Uniprot.2Q9WV75
Cellular LocalizationSecreted, extracellular space, extracellular matrix .
Tissue ExpressionExpressed in normal lung tissue but not in lung carcinoma cell lines.
Signaling_pathway
Research Areas
FunctionFunction:Cell adhesion protein that promote adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens.,similarity:Contains 1 spondin domain.,similarity:Contains 1 TSP type-1 domain.,tissue specificity:Expressed in normal lung tissues but not in lung carcinoma cell lines.,
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