Name: MINK1 Polyclonal Antibody
SKU: WP13171
Price: 268 USD
Availability: InStock

MINK1 Polyclonal Antibody

Ucallm_WP13171-50

Price range: $268.00 through $328.00

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50μl

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SKU: WP13171-100

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Product details

Background:

This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. [provided by RefSeq, Mar 2016],

Specifications

Size	50μL/100μL
Target	MAP4K6
Reactivity	Human, Mouse
Applications	WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)	150kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human MAP4K6. AA range:401-450
Specificity	MINK1 Polyclonal Antibody detects endogenous levels of MINK1 protein.
Gene Name	MINK1 MAP4K6
Protein Name	Misshapen-like kinase 1
Other Name	MINK1; / B55; / MAP4K6; / MINK; / YSK2; / ZC3; / Misshapen-like kinase 1; / GCK family kinase MiNK; / MAPK/ERK kinase kinase kinase 6; / MEK kinase kinase 6; / MEKKK 6; / Misshapen/NIK-related kinase; / Mitogen-activated protein kinase kinase kinase kinase 6
Species	Human
Gene ID	50488
Uniprot	Q8N4C8,
Species.1	Mouse
Gene ID.1	50932
Uniprot.1	Q9JM52
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Cytoplasm . Cell junction, synapse, postsynaptic density . Cell projection, axon . Cell projection, dendrite .; [Isoform 4]: Golgi apparatus.
Tissue Expression	Expressed in the brain, isoform 2 is more abundant than isoform 1. Isoform 3 is ubiquitously expressed. Isoform 1 is most abundant in the skeletal muscle. Isoform 4 is ubiquitously expressed with relative high levels in brain, skeletal muscle, pancreas and testis.
Signaling_pathway
Research Areas
Function	Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,Function:Serine/threonine kinase that may play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in the development of the brain.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 CNH domain.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed in the brain, isoform 2 is more abundant than isoform 1.,

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MINK1 Polyclonal Antibody

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MINK1 Polyclonal Antibody

Product details

Specifications

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