Name: MIPP Polyclonal Antibody
SKU: WP13174
Price: 268 USD
Availability: InStock

MIPP Polyclonal Antibody

Ucallm_WP13174-50

Price range: $268.00 through $328.00

Size

100μl

50μl

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SKU: WP13174-100

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Product details

Background:

This gene encodes multiple inositol polyphosphate phosphatase; an enzyme that removes 3-phosphate from inositol phosphate substrates. It is the only enzyme known to hydrolzye inositol pentakisphosphate and inositol hexakisphosphate. This enzyme also converts 2, 3 bisphosphoglycerate (2, 3-BPG) to 2-phosphoglycerate; an activity formerly thought to be exclusive to 2, 3-BPG synthase/2-phosphatase (BPGM) in the Rapoport-Luebering shunt of the glycolytic pathway.[provided by RefSeq, Sep 2009],

Specifications

Size	50μL/100μL
Target	MIPP
Reactivity	Human, Mouse, Rat
Applications	WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)	60kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human MINPP1. AA range:328-377
Specificity	MIPP Polyclonal Antibody detects endogenous levels of MIPP protein.
Gene Name	MINPP1
Protein Name	Multiple inositol polyphosphate phosphatase 1
Other Name	MINPP1; / MIPP; / Multiple inositol polyphosphate phosphatase 1; / 2; / 3-bisphosphoglycerate 3-phosphatase; / 2,3-BPG phosphatase; / Inositol; / 1,3,4,5; / -tetrakisphosphate 3-phosphatase; / Ins; / 1,3,4,5; / P; / 4; / 3-phosphatase
Species	Human
Gene ID	9562
Uniprot	Q9UNW1,
Species.1	Mouse
Gene ID.1	17330
Uniprot.1	Q9Z2L6,
Species.2	Rat
Gene ID.2	29688
Uniprot.2	O35217
Cellular Localization	Endoplasmic reticulum lumen .
Tissue Expression	Widely expressed with highest levels in kidney, liver and placenta.
Signaling_pathway
Research Areas	>>Glycolysis / Gluconeogenesis; / >>Inositol phosphate metabolism; / >>Metabolic pathways
Function	Catalytic activity:Myo-inositol hexakisphosphate + H(2)O = myo-inositol pentakisphosphate (mixed isomers) + phosphate.,Disease:Defects in MINPP1 may be involved in follicular thyroid tumors development.,Function:Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6) (By similarity). May play a role in bone development (endochondral ossification).,tissue specificity:Widely expressed with highest levels in kidney, liver and placenta.,

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MIPP Polyclonal Antibody

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MIPP Polyclonal Antibody

Product details

Specifications

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