MKS1 rabbit pAb
Ucallm_WP6001-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | MKS1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 61kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human MKS1 |
| Specificity | This antibody detects endogenous levels of MKS1 at Human, Mouse,Rat |
| Gene Name | MKS1 |
| Protein Name | Meckel syndrome type 1 protein |
| Other Name | |
| Species | Human |
| Gene ID | 54903 |
| Uniprot | Q9NXB0, |
| Species.1 | Mouse |
| Gene ID.1 | 380718 |
| Uniprot.1 | Q5SW45, |
| Species.2 | Rat |
| Gene ID.2 | 287612 |
| Uniprot.2 | Q499Q5 |
| Cellular Localization | Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Localizes at the transition zone, a region between the basal body and the ciliary axoneme. . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology. |
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