Product details
Background:
catalytic activity:Cleavage of 14-Ala-|-Leu-15 and 16-Tyr-|-Leu-17 in B chain of insulin. No action on collagen types I, II, IV, V. Cleaves gelatin chain alpha-2(I) > alpha-1(I)., cofactor:Binds 2 calcium ions per subunit., cofactor:Binds 2 zinc ions per subunit., domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme., function:Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase., similarity:Belongs to the peptidase M10A family.,
