Price range: $268.00 through $328.00
Background:
This gene encodes a protein belonging to the member of elastin microfibril interface-located (EMILIN) protein family. This family member is an extracellular matrix glycoprotein that can interfere with tumor angiogenesis and growth. It serves as a transforming growth factor beta antagonist and can interfere with the VEGF-A/VEGFR2 pathway. A related pseudogene has been identified on chromosome 6. [provided by RefSeq, Aug 2012],
| Size | 50μL/100μL |
| Target | MMRN2 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | |
| MW(Observed) | 105kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human MMRN2 AA range: 133-183 |
| Specificity | This antibody detects endogenous levels of MMRN2 at Human/Mouse |
| Gene Name | MMRN2 EMILIN3 |
| Protein Name | MMRN2 |
| Other Name | Multimerin-2; / EMILIN-3; / Elastin microfibril interface located protein 3; / Elastin microfibril interfacer 3; / EndoGlyx-1 p125/p140 subunit |
| Species | Human |
| Gene ID | 79812 |
| Uniprot | Q9H8L6, |
| Species.1 | Mouse |
| Gene ID.1 | 105450 |
| Uniprot.1 | A6H6E2 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted, extracellular space, extracellular matrix . |
| Tissue Expression | Endothelium. |
| Signaling_pathway | |
| Research Areas | |
| Function | PTM:N- and O-glycosylated.,similarity:Contains 1 C1q domain.,similarity:Contains 1 EMI domain.,subunit:Heteromer of p110, p125, p140 and p200 subunits; disulfide-linked.,tissue specificity:Endothelium., |
