MOCS2B rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | MOCS2 |
| Reactivity | Human |
| Applications | WB |
| MW(Calculated) | 10kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human MOCS2B |
| Specificity | This antibody detects endogenous levels of MOCS2B at Human |
| Gene Name | MOCS2 MOCO1 |
| Protein Name | Molybdopterin synthase sulfur carrier subunit (MOCO1-A) (Molybdenum cofactor synthesis protein 2 small subunit) (Molybdenum cofactor synthesis protein 2A) (MOCS2A) (Molybdopterin-synthase small subunit) (Sulfur carrier protein MOCS2A) |
| Other Name | |
| Species | Human |
| Gene ID | 4338 |
| Uniprot | O96033, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9Z224 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm, cytosol . |
| Tissue Expression | Widely expressed. Highest levels are found in heart and skeletal muscle. Lower levels are present in brain, kidney and pancreas. Very low levels are found in lung and peripheral blood leukocytes. |
| Signaling_pathway | Genetic Information Processing >> Folding, sorting and degradation >> Sulfur relay system |
| Research Areas | |
| Function | Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin. |
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