SKU: WP8639 Categories: ,

MOCS2B rabbit pAb

Price range: $268.00 through $328.00

SKU: WP8639-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetMOCS2
ReactivityHuman
ApplicationsWB
MW(Calculated)10kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human MOCS2B
SpecificityThis antibody detects endogenous levels of MOCS2B at Human
Gene NameMOCS2 MOCO1
Protein NameMolybdopterin synthase sulfur carrier subunit (MOCO1-A) (Molybdenum cofactor synthesis protein 2 small subunit) (Molybdenum cofactor synthesis protein 2A) (MOCS2A) (Molybdopterin-synthase small subunit) (Sulfur carrier protein MOCS2A)
Other Name
SpeciesHuman
Gene ID4338
UniprotO96033,
Species.1Mouse
Gene ID.1
Uniprot.1Q9Z224
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm, cytosol .
Tissue ExpressionWidely expressed. Highest levels are found in heart and skeletal muscle. Lower levels are present in brain, kidney and pancreas. Very low levels are found in lung and peripheral blood leukocytes.
Signaling_pathwayGenetic Information Processing >> Folding, sorting and degradation >> Sulfur relay system
Research Areas
FunctionActs as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.
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